Verbascum Thapsus (Mullein) Versatile Polarity Extracts: GC-MS Analysis, Phytochemical Profiling, Anti-bacterial Potential and Anti-oxidant Activity

نویسندگان

چکیده

Verbascum thapsus is naturally grown in the Himalayas and widely used herbal teas traditional medicine for its anticarcinogenic anti-inflammatory properties. The present study was designed to majority of leaf extracts from thapsus. All were analysed phytochemical properties, antioxidant capacity antimicrobial potential against both Gram-positive Gram-negative bacteria. Biochemical investigations GC-MS analysis identifying phytochemicals. DPPH assay, Kirby’s Disc Diffusion method (KDM), 96 well test, Resazurin test performed investigation. Results indicate that verbascum Pakistan rich alkaloids phenols. Noteworthy antibacterial activity observed S. sonnei, L. lactis, B. subtilis, C. freundii, K. oxytoca, monocytogenes, enterica. GCMS analyses V. revealed presence medically important bio compounds including Hexadecanoic acid, methyl es Stigmasterol (antibacterial activity), 2(5H)-Furanone (appetite suppressant), 3-Hydroxy-.beta.-damascone (anti-inflammatory properties), Squalene (antiaging, anti-inflammatory, anti-acne, eczema), Vitamin E 2-Methoxy-4-vinylphenol (antioxidants). Antioxidant radical scavenging determined acetone extract This concludes remarkable Thapsus

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ژورنال

عنوان ژورنال: Pharmacognosy Journal

سال: 2021

ISSN: ['0975-3575']

DOI: https://doi.org/10.5530/pj.2021.13.189